Georgia Tech inventors from the Department of Biomedical Engineering have developed a microparticle delivery system formed via water and oil emulsion and free radical polymerization. The cross-linking of functionalized heparin within the micro-particle allows for the loading and release of positively-charged proteins, as well as variety of small molecules. The polymers utilized also allow for the degradation time course of the particle to be finely tuned.
- Deliverable via standard needles and syringes
- Tunable release & degradation
- Possibility of co-delivery of small molecules and proteins
- Improved material stability and efficacy
- Medicinal fields requiring sustained release of molecules
Preparing small molecules and proteins for injection is essential for progress in many medicinal fields. However, the science thus far has been restricted by the size and charge of the molecules, as well as maintaining their activity. In addition, many systems require complex and/or expensive injection tools, and the timed release of the medicine throughout the body is difficult to control.